Stillbirth and fetal growth restriction

نویسندگان

چکیده

Aim: to estimate the rate of early-onset and late-onset fetal growth restriction (FGR) in stillbirth, identify features placentaassociated complications determine respective risk factors stillbirth (especially at early gestational age). Materials Methods. There were retrospectively studied 61 cases 2016–2019 that occurred III level obstetric hospitals: 32 (23–31 weeks gestation) late (32–39 weeks) cases; 156 live births with 8–10 Apgar scores delivered 36–41 gestation used as controls. Quantitative parameters compared using mean values standard deviation; nominal analyzed odds ratio (OR) adjusted OR (aOR) 95 % confidence interval (CI). Results. More than half stillbirths are associated FGR almost 60 phenotype this pathology. Both births, 2/3 have extremely low weight (OR = 1.8; CI 0.6–6.9); 1/3 restricted fetuses detected shortly before delivery 1.3; 0.7–2.4); 1/4 pregnancies complicated by placental insufficiency not 1.4; 0.7–2.7). Risk pregnancy (aOR 3.2; 1.0–10.3), maternal age over 28 years 6.0; 1.2–29.4), miscarriages multiple induced abortions 3.6; 1.1–11.2), non-compliance regular clinics visiting correction threatening conditions 10.9; 1.3–91.6), toxoplasma infection 1.5–24.5). Early is an older mother's 5.8; 1.0–34.4), greater parity 3.3; 1.0–10.4), uterine diseases including endometrial polyps, endometriosis, cervix cervicitis, dysplasia 4.0; 0.9–17.2), diabetes mellitus 3.1; 0.8–13.2) preeclampsia. Conclusion. The comprises twice higher birth, being less 30 %. In also prevails. no prominent for previously known regardless hypotrophy. vs. more gynecological pathologies well

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Altered fetal growth, placental abnormalities, and stillbirth

BACKGROUND Worldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk factors for stillbirth. The aim of this study was to identify patterns of association between placental abnormalities, fetal growth, and stillbirth. METHODS AND FINDINGS Population-based case-control study of all stillbirths a...

متن کامل

Stillbirth classification in population-based data and role of fetal growth restriction: the example of RECODE

BACKGROUND Stillbirth classifications use various strategies to synthesise information associated with fetal demise with the aim of identifying key causes for the death. RECODE is a hierarchical classification of death-related conditions, which grants a major place to fetal growth restriction (FGR). Our objective was to explore how placement of FGR in the hierarchy affected results from the cla...

متن کامل

Neurodevelopment after fetal growth restriction.

Fetal growth restriction (FGR) can emerge as a complication of placental dysfunction and increases the risk for neurodevelopmental delay. Marked elevations of umbilical artery (UA) Doppler resistance that set the stage for cardiovascular and biophysical deterioration with subsequent preterm birth characterize early-onset FGR. Minimal, or absent UA Doppler abnormalities and isolated cerebral Dop...

متن کامل

Early onset fetal growth restriction

Fetal growth restriction (FGR) diagnosed before 32 weeks is identified by fetal smallness associated with Doppler abnormalities and is associated with significant perinatal morbidity and mortality and maternal complications. Recent studies have provided new insights into pathophysiology, management options and postnatal outcomes of FGR. In this paper we review the available evidence regarding d...

متن کامل

Diagnosis and Management of Fetal Growth Restriction

Fetal growth restriction (FGR) remains a leading contributor to perinatal mortality and morbidity and metabolic syndrome in later life. Recent advances in ultrasound and Doppler have elucidated several mechanisms in the evolution of the disease. However, consistent classification and characterization regarding the severity of FGR is lacking. There is no cure, and management is reliant on a stru...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Obstetrics, Gynecology and Reproduction

سال: 2023

ISSN: ['2313-7347', '2500-3194']

DOI: https://doi.org/10.17749/2313-7347/ob.gyn.rep.2023.357